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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK5RAP2 All Species: 9.7
Human Site: S1173 Identified Species: 26.67
UniProt: Q96SN8 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96SN8 NP_001011649.1 1893 215024 S1173 G E E M T F S S L H Q V R Y V
Chimpanzee Pan troglodytes Q19UN5 1893 214874 S1173 G E E M T F S S L H Q V R Y V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_855524 1859 208670 S1170 E E E M T F S S L H R V R Y V
Cat Felis silvestris
Mouse Mus musculus Q8K389 1822 205926 L1124 L K Q K I H D L Q T E L E G Y
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90631 1364 155958 A688 E Q L R E E L A Q T V N T K E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687560 1559 174686 L883 L R G A L E D L L Q P T D M H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54623 1320 149502 E643 A E Y M R A L E R N K L L Q R
Honey Bee Apis mellifera XP_392107 1375 159683 T699 G R N K S D V T Q E S A T A Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791309 2356 267481 K1379 Q N L I E L L K R H I H L N G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 N.A. 71.4 N.A. 68.4 N.A. N.A. N.A. 20 N.A. 22.3 N.A. 21.1 22.5 N.A. 21.8
Protein Similarity: 100 99.2 N.A. 80.6 N.A. 78.1 N.A. N.A. N.A. 38.6 N.A. 39.8 N.A. 39.3 39.6 N.A. 40.3
P-Site Identity: 100 100 N.A. 86.6 N.A. 0 N.A. N.A. N.A. 0 N.A. 6.6 N.A. 13.3 6.6 N.A. 6.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 26.6 N.A. N.A. N.A. 13.3 N.A. 6.6 N.A. 33.3 20 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 12 0 12 0 12 0 0 0 12 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 12 23 0 0 0 0 0 12 0 0 % D
% Glu: 23 45 34 0 23 23 0 12 0 12 12 0 12 0 12 % E
% Phe: 0 0 0 0 0 34 0 0 0 0 0 0 0 0 0 % F
% Gly: 34 0 12 0 0 0 0 0 0 0 0 0 0 12 12 % G
% His: 0 0 0 0 0 12 0 0 0 45 0 12 0 0 12 % H
% Ile: 0 0 0 12 12 0 0 0 0 0 12 0 0 0 0 % I
% Lys: 0 12 0 23 0 0 0 12 0 0 12 0 0 12 0 % K
% Leu: 23 0 23 0 12 12 34 23 45 0 0 23 23 0 0 % L
% Met: 0 0 0 45 0 0 0 0 0 0 0 0 0 12 0 % M
% Asn: 0 12 12 0 0 0 0 0 0 12 0 12 0 12 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % P
% Gln: 12 12 12 0 0 0 0 0 34 12 23 0 0 12 12 % Q
% Arg: 0 23 0 12 12 0 0 0 23 0 12 0 34 0 12 % R
% Ser: 0 0 0 0 12 0 34 34 0 0 12 0 0 0 0 % S
% Thr: 0 0 0 0 34 0 0 12 0 23 0 12 23 0 0 % T
% Val: 0 0 0 0 0 0 12 0 0 0 12 34 0 0 34 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 12 0 0 0 0 0 0 0 0 0 0 34 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _